Polyphenols or bioflavonoids found in grape seed extract protect the heart and promote healthy veins, arteries and capillaries. An important subgroup of polyphenols in grape seed are leucoanthocyanins or proanthocyanidins. These flavonoids help to strengthen blood vessels, increasing their tone and elasticity while, enhancing the effects of vitamin C against free radicals. Grape seed extract may help allergy sufferers because the leucoanthocyanins help inhibit histamine release, suppressing allergy symptoms. Natural Factors Grape Seed Extract is standardized to contain 85 to 95% leucoanthocyanins (proanthocyanidins), bound to phosphatidylcholine from lecithin for optimum absorption.